精子染色體異常的機率增加，會影響以下三個層面：
胚胎：
Rodrigo et al., 2010
孕期：
Rubio et al., 2001.
後代：
這項技術僅能夠偵測本次檢體的染色體非整倍性。在極少數射精樣本或睾丸樣本中，將可能沒有足夠的精子來正確估計非整倍體的風險。
Rodrigo L, Peinado V, Mateu E, Remohí J, Pellicer A, Simón C, Gil-Salom M, Rubio C. Impact of different patterns of sperm chromosomal abnormalities on the chromosomal constitution of preimplantation embryos. Fertil Steril. 2010 Sep; 94(4):1380-6.
Rubio C, Gil-Salom M, Simón C, Vidal F, Rodrigo L, Mínguez Y, Remohí J, Pellicer A. Incidence of sperm chromosomal abnormalities in a risk population: relationship with sperm quality and ICSI outcome. Hum Reprod. 2001 Oct; 16(10):2084-92.
Rodrigo L, Mateu E, Mercader A, Cobo A, Peinado V, Milán M, Al-Asmar N, Campos-Galindo I, García-Herrero S, Mir P, Simón C, Rubio C. New tools for embryo selection: comprehensive chromosome screening by array comparative genomic hybridization. BioMed
Research International. 2014; In Press.
