精子染色體異常檢測( Sperm Aneuploidy Test )是一項診斷檢測，用於檢查男性不育的遺傳病因。
它能夠評估精子中異常數量的染色體（非單倍體和二倍體）的存在。
通過螢光原位雜合技術，分析常見造成流產和影響後代的13,18, 21, X 和 Y 染色體數目是否正常
精子染色體異常的機率增加，會影響以下三個層面：
胚胎:
Rodrigo et al., 2010.
孕期:
Rubio et al., 2001.
後代:
Rodrigo L, Peinado V, Mateu E, Remohí J, Pellicer A, Simón C, Gil-Salom M, Rubio C. Impact of different patterns of sperm chromosomal abnormalities on the chromosomal constitution of preimplantation embryos. Fertil Steril. 2010 Sep; 94(4):1380-6.
Rubio C, Gil-Salom M, Simón C, Vidal F, Rodrigo L, Mínguez Y, Remohí J, Pellicer A. Incidence of sperm chromosomal abnormalities in a risk population: relationship with sperm quality and ICSI outcome. Hum Reprod. 2001 Oct; 16(10):2084-92.
Rodrigo L, Mateu E, Mercader A, Cobo A, Peinado V, Milán M, Al-Asmar N, Campos-Galindo I, García-Herrero S, Mir P, Simón C, Rubio C. New tools for embryo selection: comprehensive chromosome screening by array comparative genomic hybridization. BioMed
Research International. 2014; In Press.
